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Depletion of which of the following molecules from the mitochondria will most directly inhibit NAD+.
Molecule that inhibit concentrations of ATP, acetyl-CoA, and NADH that are indicated as high level of energy supply. The molecule produced in the reaction like citrate, can also act as an inhibitor of the reaction.
In general ,Oxidation of fats and carbohydrates, also in the citric acid cycle, NAD+ is reduced to NADH. NADH generally moves across into the mitochondria, where NADH is oxidized through the electron transport chain for ATP generation.
To learn more about NAD+ , here
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