The release of myoglobin into the blood, caused by an electrical burn, can result in failure of?

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01-08-2022
Biology

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The release of myoglobin into the blood, caused by an electrical burn, can result in failure of?

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shaikhmohd0119 shaikhmohd0119 · Answer 1 · 2022-08-05T08:50:05-04:00

The release of myoglobin into the blood, caused by an electrical burn, can result in failure of the kidneys.

How does myoglobin result in kidney failure?

Myoglobin protein is present in the striated muscles including skeletal and heart muscles. Unbound myoglobin when released into the blood can lead to renal (kidney) failure.
Myoglobin is a heme- containing protein that binds to oxygen and supplies oxygen to the muscle cells (myocytes) for energy.
When in blood, myoglobin can damage kidneys by resulting in intrarenal vasoconstriction, injury or obstruction to renal tube.
Levels of myoglobin can increase due to heart attack, muscle injury and damage. This in turn leads to kidney failure.
Myoglobin can result in increase in potassium levels in blood which disturbs the rhythm of heart.

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How does myoglobin result in kidney failure?

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