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If digoxin has a half life of 35 hours how long will it take for a toxic plasma concentration of 8ng/ml to decline to a therapeutic plasma concentration of 2ng/ml

Sagot :

Digoxin is a medication for treating erratic heartbeats.

What is digoxin's primary effect?

By preventing the activity of the enzyme (ATPase) that regulates the entry of calcium, sodium, and potassium into the heart muscle, digoxin enhances the force of the muscle's contraction.

With a bioavailability of between 75% and 95%, digoxin is swiftly absorbed from the gastrointestinal tract. Its half-life is 36–48 hours in persons with normal renal function and 3.5–5 days in anuric patients because it is mostly removed by the kidneys.

Learn more about digoxin here:

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