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ACh must be cleared from the synaptic cleft quickly after it is released, to prevent constant muscle stimulation. How is ACh cleared quickly from the synaptic cleft?
- It is broken down by an enzyme and recycled back into vesicles in the synaptic terminal.
- It is taken up by the muscle when it attaches to receptors on the motor endplate.
- It slowly diffuses away from the synaptic cleft.


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