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Sagot :
Glut4 transporters are groups of inserted into the plasma membrane in response to glucagon.
GLUT4 is an insulin-regulated glucose transporter that is answerable for insulin-regulated glucose uptake into fat and muscle cells. within the absence of insulin, GLUT4 is especially found in intracellular vesicles called GLUT4 garage vesicles (GSVs).
GLUT4 is insulin-responsive glucose transporter, determined within the skeletal muscle, heart, adipose tissue, and brain. GLUT4 is present in vesicles within the cytoplasm of the cells. The binding of insulin to insulin receptors reasons the translocation of GLUT4 to the cellular membrane. The mechanism for GLUT4 is an example of a cascade effect, wherein the binding of a ligand to a membrane receptor amplifies the sign and causes a cellular response. In this situation, insulin binds to the insulin receptor in its dimeric shape and activates the receptor's tyrosine-kinase area.
Learn more about GLUT4 here:
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