The structure of nucleic acids, DNA and RNA, differ in that

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a
DNA contains a nucleotide with thymine, while RNA contains a nucleotide with uracil.
b
DNA's nucleotide sequence is single stranded, while RNA's nucleotide sequence is double stranded.
c
RNA's backbone is made up of phosphates, while DNA's backbone is made up of nitrates.
d
RNA contains only three different nucleotides, while DNA contains four different nucleotides.